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8th February 2010

Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective by Maurice E. Langham

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Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective | Springer | English | 2009-04-01 | ISBN: 0387097155 | 192 pages | PDF |

The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 years on the physiology of intraocular pressure, ocular blood flow and the relation of these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the author’s own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby led to new methods of diagnosis and therapy.

From the reviews:
"This monograph is primarily an extensive review of the literature on intraocular pressure and any other pressures having to do with the eye. … A major value of this monograph is the wealth of primary citations to literature that predates PubMed. … this monograph could have used some anatomical figures and diagrams in the beginning chapters to go along with the physiological descriptions because the monograph is very approachable to interested readers who may not be currently working in the eye." (Joseph C. LaManna, Journal of Alzheimer’s Disease, Vol. 18, 2009)

"Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective summarizes a life’s work dedicated to understanding how a complex interaction of factors, such as intraocular pressures, ocular perfusion, and autoregulation affect ocular health. As such, this sole-authored text explores the … interests of most practicing ophthalmologists and neuroradiologists. … The illustrations, graphs, and line drawings have been carefully selected and help the author present a compelling story of the value of this approach to understanding the pathophysiology of ocular disease." (American Journal of Neuroradiology, September, 2009)


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